Okay, *this* is my final Riley Riddle (and not my [previous](https://puzzling.stackexchange.com/questions/72014/my-final-song-to-riley) one), because I could not resist... <br> ...and that meant this had to be even better.

>>**Riddle me this:**

>*My prefix will pray with an S, <br> My suffix is red with an A, <br> My infix, so ill with an F, <br>If only affixed with an E. <br> <br> Because the answer is SAFE.*

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**Note:**

> The answer is **not** "safe / SAFE". This is genuinely true; no wordplay involved.