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The clue is:

One caregiver in particular turned indifferent. (9)

I think the answer may be "alienated" but I can't really explain it. Can anyone else provide a good explanation?

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Explanation

"One" = A
"caregiver" = EN (Enrolled Nurse)
"particular" = DETAIL (as a noun, they are synonyms)
"particular turned" = LIATED
"caregiver in particular turned" = LI(EN)ATED
"One caregiver in particular turned" = A+LI(EN)ATED
"indifferent" is then the definition

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    $\begingroup$ Where in the world is EN a common abbreviation? $\endgroup$
    – Chris Cudmore
    Mar 16, 2020 at 13:00
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    $\begingroup$ @ChrisCudmore I found a few references to this: here, here and here. Seems to be used in Australia, New Zealand, Canada and the UK although, I'll admit, it's a less well know acronym. $\endgroup$
    – hexomino
    Mar 16, 2020 at 14:04
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    $\begingroup$ Never heard it in Canada. We use RN for Registered Nurse. $\endgroup$
    – Chris Cudmore
    Mar 16, 2020 at 16:46
  • $\begingroup$ @ChrisCudmore actually, my mistake, it seems in Canada "enrolled nurses" are referred to as "graduate nurses", see here $\endgroup$
    – hexomino
    Mar 16, 2020 at 16:50
  • $\begingroup$ @ChrisCudmore In general, enrolled nurses are second-level nurses who work under registered nurses but are sometimes called by different names in different countries. $\endgroup$
    – hexomino
    Mar 16, 2020 at 16:57

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