The clue is:

One caregiver in particular turned indifferent. (9)

I think the answer may be "alienated" but I can't really explain it! Anyone?

• Has a correct answer been given? If so, please don't forget to $\color{green}{\checkmark \small\text{Accept}}$ it :) – Rubio Mar 17 at 12:09

Explanation

"One" = A
"caregiver" = EN (Enrolled Nurse)
"particular" = DETAIL (as a noun, they are synonyms)
"particular turned" = LIATED
"caregiver in particular turned" = LI(EN)ATED
"One caregiver in particular turned" = A+LI(EN)ATED
"indifferent" is then the definition

• Where in the world is EN a common abbreviation? – Chris Cudmore Mar 16 at 13:00
• @ChrisCudmore I found a few references to this: here, here and here. Seems to be used in Australia, New Zealand, Canada and the UK although, I'll admit, it's a less well know acronym. – hexomino Mar 16 at 14:04
• Never heard it in Canada. We use RN for Registered Nurse. – Chris Cudmore Mar 16 at 16:46
• @ChrisCudmore actually, my mistake, it seems in Canada "enrolled nurses" are referred to as "graduate nurses", see here – hexomino Mar 16 at 16:50
• @ChrisCudmore In general, enrolled nurses are second-level nurses who work under registered nurses but are sometimes called by different names in different countries. – hexomino Mar 16 at 16:57