Create a pangram sentence by replacing the 26 dots with the 26 letters of the alphabet (different dots, different letters):
... .A.. ..C.. .U..K .H.. ...ES .U.. O.E. ..EM
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big lAzy duCks qUacK wHen foxES jUmp OvEr thEM
The first place my mind goes when someone says "pangram" is to those jumping foxes. The letters given in quack, jump, and over were especially helpful getting this one started.