Inspired from a puzzle marathon, here is a math puzzle. There is a pattern with this set of numbers (not in the creation though). According to the pattern, what is the logical replacement for the question marks?
$$\begin{align} 3 & 5 & 1 & 6 & 8 & 2 \\ 1 & 3 & 1 & 3 & 3 & 1 \\ \\ 5 & 1 & 3 & 8 & 1 & 4\\ 7 & 2 & 1 & 2 & 2 & 9\\ \\ 6 & 7 & 3 & 2 & 4 & 1\\ ? & ? & 5 & 3 & 8 & 2\\ \end{align}$$