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My prefix? A choice always off'ring the best.
My suffix? An action afflicting the rest.
My infix? Detectives that take me to test,
And speak me out loud, where oft I'm at my best.

Hint:

I'm wondering where wonderful words went.

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I think the answer is:

Alliteration

My prefix? A choice always off'ring the best.

All means that you get everything. I.e, All-inclusive or "A" is normally the best, A ranked restaurants or A as a grade. EDIT-OP: also, you choose the first letter, the 'prefix,' of a sentence using alliteration.

My suffix? An action afflicting the rest.

-tion is a suffix that forms nouns of action or condition. EDIT-OP: or "shun," as in "shunning all other letters"

My infix? Detectives that take me to test,

Liter, I guess you could test a milliliter of blood OR @Statman's suggestion, Literati: Detectives are well educated and might look things up in books

And speak me out loud, where oft I'm at my best.

Alliterations sounds the best when you say them out loud. They roll off the tongue nicely.

Hint:

The hint is an alliteration: I'm wondering where wonderful words went.

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    $\begingroup$ This sounds right. Here's an alternative suggestion for the infix: rot13(yvgrengv) $\endgroup$ – Statman Mar 29 '18 at 14:15
  • $\begingroup$ The answer is right, the justifications aren't what I had in mind (though @Statman 's was!). The prefixes of {the answer] was what I was alluding to, similar to an Acrostic. Any other ideas for the suffix? $\endgroup$ – Chowzen Mar 29 '18 at 14:56
  • $\begingroup$ Didn't realize that was a word @Statman thanks! $\endgroup$ – Sensoray Mar 29 '18 at 14:56
  • $\begingroup$ Even smaller...rot13(gur cersvk pubbfrf "n" be "j", naq ????f gur erfg). $\endgroup$ – Chowzen Mar 29 '18 at 15:05
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I think that the answer is:

Superconducting

My prefix? A choice always off'ring the best.

Super- means above, over, etc.

My suffix? An action afflicting the rest.

-ducting - means to convey or channel by means of a duct or ducts. The superconductor conducts electricity. A system of ducts can conduct a lot of other things.

My infix? Detectives that take me to test,

-con- The cops will definitely be putting to the test something they suspect is a con operation.

And speak me out loud, where oft I'm at my best.

And a superconductor is the best possible conductor.

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  • $\begingroup$ No, sorry. The detectives "take me to test and speak me out loud." $\endgroup$ – Chowzen Mar 27 '18 at 14:25

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