My first is a journey on the sea
At the resistance should my second be
Third is a short little, drawing knot
Backwards in the clock the fourth I spot

Hint:

Obviously, the title contains a big hint. And wosquaddle is quite understandable. But what is pho? What clue might contain -pho-?

UPDATE 23/7
Since this is incredibly difficult, I guess I must reveal the main idea of the puzzle.

Puzzled Pig's guess about -pho- is correct! They are indeed homophones. All of the 4 words have real meanings, however, none of them is mentioned (even implicitly) in the riddle. Instead, there is a meaning for a word (or phrase) which sounds the same as the word in the word-square.

• "But what is pho?" Pho is a Vietnamese noodle soup. :P – feelinferrety Jul 21 '17 at 23:35

I think I might be onto the right square, but the explanation might not be complete.

S A L E
A T O M
L O T I
E M I T

[Edit: Initial guess for line 3 was LOKI]

Explanation:

1. A homophone of journey on the sea (Sail);

2. A soundalike of At the resistance = At+Ohm (unit of resistance);

3. The one I'm struggling with a bit; the god Loki is a homophone, of Low-key, which kind of fits 'short' and 'little', but I'm not sure what a drawing knot is [Edit: Actually, I got a letter wrong here. This word should be LOTI, the plural of lotus and a homophone of Low + Tie ('short' & 'knot'), as per the OP's explanation in the comments];

4. Backwards in the clock = The word Time spelled backwards, but it's not really a homophone.

• Short = little = 'low', draw = knot = 'tie'. The homophone of it is "LOTI" the plural of lotus. The rest is correct! – William Nathanael Jul 29 '17 at 1:24
• Ah... shucks. Thanks for explaining, though! Glad I was mostly on target ;) – Walt Jul 29 '17 at 15:31
• @Walt Give it the green check, then! – feelinferrety Jul 31 '17 at 14:43
• @feelinferrety Well, I'm not the OP. ;) But I fixed the answer according to the OP's original intention. – Walt Aug 19 '17 at 14:27
• Gah, stupid. I picked the wrong W for the auto tagging. U_U – feelinferrety Aug 20 '17 at 15:07

It doesn't really fit but might get a bit of discussion going:

S A I L
A E R O
I R I S
L O S T

I feel there may be something I'm missing to do with:

The lack of rhyme between lines 3 and 4 and the somewhat unusual title

Edit: Also had this one almost:

O R C A
R E N
C E L T
A N T I

• Well an iris is kind of a knot like muscle that draws itself together and you can be lost in time. As I said doesn't really fit much at all but might point someone in the right direction. – James Coyle Jul 16 '17 at 12:47
• The title seems like a shortened version of "Four word square riddle" – Christoph Jul 16 '17 at 12:50
• Ah that makes sense! – James Coyle Jul 16 '17 at 12:52
• All 4 words are wrong :p Sorry for the bad rhyme, I'll try to improve it when I have time. By the way, @Christoph got the title wrongly interpreted. If this is too hard, I'll probably change the title later on. – William Nathanael Jul 16 '17 at 13:29
• In that case I'm guessing there is more to this than one would initially think. I thought for sure sail would be correct... The title appears to have the R and letter after removed from each word so that could hint to the answer being words with R? removed eg. cruise -> cise. I can't really see anything else that will let me piece this one together at the moment. Hopefully someone else can make some more progress. – James Coyle Jul 16 '17 at 14:11