There are 50 different possible ways that the unknown mines next to the revealed region could be configured:

Here, the green cells are clear (no mines), while the X's around the perimeter indicate the different ways the mines could potentially be placed.
If we consider each of these to be of equal probability (probably not quite true, because the total number of mines on the board might mean that configurations with more (or less) mines are slightly more (or less) probable), then we simply need to count the number of configurations with a mine in each location to determine the probability of finding a mine there.
Doing so, we end up with

From this, it seems evident that the best move is on the fifth row, where there is an 8. Making this move gives you only a 16% chance ($\frac8{50}$) of finding a mine.
Conversely, picking one of the bottom squares means you have a 66% chance ($\frac{33}{50}$) of finding a mine.
Obviously, the other option is to pick a random non-adjacent square, and hope to get lucky.
There are 25 squares revealed, and an additional 13 squares adjacent to those, for a total of 38. Subtract that from 480 total squares, and we have 442 potential "guesses".
There have been 5 of 99 mines revealed already, and there could be anywhere from 4 to 7 mines in the adjacent squares. To give our best shot at a random guess, let's assume there are 7 mines adjacent, leaving us with 87 mines in the non-adjacent area.
That means that picking a random non-adjacent square will give us an $\frac{87}{442} \approx 0.1968$ or 19.7% chance of finding a mine, which is still worse than our best-case 16% above.