This is NOT a number sequence puzzle

Question

Since everyone is trying their hand at this type of puzzle, I've decided to create a number seq -

We interrupt your Puzzle Solving Entertainment to inform you of this Public Service Exclamation:
This is NOT a number sequence puzzle, although you will be finding a number from a series of numbers.
If you're looking down upon this sequence, I'll tell you that it's a very basic puzzle.

-uence looking puzzle that isn't actually a number sequence.

565, 721, 575, 425, 667 => 4??

(EDIT: The fourth number should have been 4TWO5 not 415!!! Super sorry for the inconvenience)

Answer 1

The number is

416

---

As @MikeQ and @boboquack noted in the comments,

The italicised letters are ioi iio ioi, which, when taking "basic" aka hint to binary", leads to 565, the first number in the "sequence". In addition, each line in the blockquote has three italicised letters, confirming this interpretation.

If we then do this for each number, we get

101 110 101
111 010 001
101 111 101
100 010 101
110 110 111
formatting according to the "looking down upon this sequence" hint.

Now, we want three digits, and our grid is neatly split into three blocks, but none look particularly like a digit. However, with some nudging from the OP,

we can re-group the bits so that all the fours bits are together, all the twos bits are together, and all the ones bits are together. For example, looking at the first row, the fours bits from left to right are 1__ 1__ 1__, the twos bits are _0_ _1_ _0_, and the ones bits are __1 __0 __1. We can put them together to form 111 010 101.

Doing so for each row yields

111 010 101
100 110 101
111 010 111
101 010 001
111 111 001

If you can't see it yet:

*** * * *
* ** * *
*** * ***
* * * *
*** *** *

That doesn't start with a 4 though.

Let's flip it. (Or, more technically, take the bits in little endian order).
* * * ***
* * ** *
*** * ***
..* * * *
..* *** ***