Related: Connect 4 Recursive
We have a mega tic tac toe grid. Each of the nine cells of the mega grid has a smaller tic tac toe grid. In total we have 81 cells that can be filled. (Maybe imagine a Sudoku grid)
Alice starts by playing in any of the 81 squares. Now the grid in which the next player plays is determined by the previous move by the opponent. For example, suppose Alice plays in the top right corner cell of the grid at the top left corner of the mega grid. Now Bob has to play in the grid at the top right corner of the mega grid. He can play in any of the nine spaces there. If he, say, plays in the centre of that grid, Alice will have to play in the centre grid (but she choose which cell in it).
If a player gets three in a row in one of the nine grids, he/she is considered the winner of the grid and gains a point. Play however continues as per same rules. Any more three in a rows formed in the same grid are not counted or awarded points.
If a player is directed to a grid that already has all 9 cells filled, he/she can choose to play in any cell in any other grid (kind of the way Alice starts). Play continues as normal.
Play ends when all cells are filled (or the more likely instance when a player wins 5 points, and further play is pointless). Player with the most points wins.
If Alice and Bob play perfectly, who wins?
P.S. I spent some time on this, and while I feel the game is highly biased towards Alice, I wasn't able to find a simple enough strategy.
Listing out of cases (maybe even by computer) may be required.
P.S.2 Computer programs are allowed, but it would be better to use them only as means to gain human-comprehendable insight.
There exists a simple no-computers solution, which has been posted.