I'm working on creating a crossword puzzle and am unfortunately stuck with the combination ~CY~E (blank C Y blank E). Does anyone have any PC phrases or words that could fit that combination?
Nothing particularly likely - I'd try to change one of the crossing words instead.
The suffix -cyte means cell, so you could be cute and have it be ACYTE with the clue "Cell for sore eyes"
Rotate the string:
Instructing someone to freeze ('icy be'), or saying one is frozen ("Icy me")?
If the puzzle is using cryptics, perhaps an abbreviated institution got mixed up with a yes-man (ACYOE interleaves "CO" and "AYE")?
If you really have to use those letters, I think you're going to have to settle for obscure words.
It's poor form, but you could use
After shuffling, my ace let me get ahead (1, 4)
anag. MYACE = A CYME
a head (of unexpanded leaves) = a cyme
Ocyte is a less common spelling for oocyte - egg cell. Would that work?