I'm a natural in math.
The variants of numbers to solve me don't go higher than 100 and 26.
What am I?
53 61 23 41 11
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The solution is
The method for solving is:
First realise that all the numbers are prime.
Convert each prime to the index of the prime, e.g. $53 \to 16$ because $53$ is the 16th prime.
You get: $16\;18\;9\;13\;5$
Converting this using $a=1,b=2,\ldots,z=26$ you get the solution PRIME.