You have 4 options to guess what the question mark in the middle is.
Please try to solve without the hint first
There are 3 commonalities for all the words
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I've been thinking for some time that the answer to this is:
4. THE BEST OF BOTH WORLDS
These clues point to words that have specific letters in common with the names of the planets (i.e. worlds) in our solar system.
However, whenever I think I've pinpointed the specific rule, it seems that one of my words produces an exception, so I'm not 100% sure I have identified all of them exactly correctly. Here are my contenders though:
A SURICATE = MEERKAT
A BAD NEWS FOR COMPUTERS = VIRUS
WHERE WE ARE = EARTH
WHAT SOLDIERS SOMETIMES DO = MARCHES
ONE OF THE DOZEN DECIDERS = JURYSPEAKER
A METAL FASTNER AND PIERCER = SAFETYPIN
THE ARMPITS = UNDERARMS
A DIRECTION = NORTHERN HEMISPHERE?
With these word choices we can see that:
1. Every word begins with the same letter as the respectively ordered planet:
Meerkat/Mercury, Virus/Venus, Earth/Earth, Marches/Mars, Juryspeaker/Jupiter, Safetypin/Saturn, Underarms/Uranus, NorthernHemisphere/Neptune.
2. Not only that, but every word (except Virus) also contains the second and third letters of the respectively ordered planet:
MEeRkat/MERcury, [Virus/Venus], EARth/EARth, MARches/MARs, JUrysPeaker/JUPiter, SAfeTypin/SATurn, UndeRArms/URAnus, NorthErnHemisPhere/NEPtune.
3. Additionally, every word (except Meerkat) ends with the same letter as the respectively ordered planet:
[Meerkat/Mercury], ViruS/VenuS, EartH/EartH, MarcheS/MarS, JuryspeakeR/JupiteR, SafetypiN/SaturN, UnderarmS/UranuS, NeptunE/NorthernHemispherE.
Criticisms of my approach:
A) Clearly, 'MEERKAT' and 'VIRUS' are exceptions to these rules - I may not yet have these correct. (Could 'Meerkatty' be correct instead? No clue yet as to a suitable 'Virus' alternative though...)
B) 'Northern Hemisphere' is not really 'a direction', but given that I was able to find words containing the first three letters of each of the other planets, this is the closest I have for words of the form n*e*p*e
C) I have 'Earth' for both the planet and its substitute word, rendering it trivially true for all the rules - this may not be the OP's intention...
These things considered, I am positive that MARCHES, JURYSPEAKER, SAFETYPIN and UNDERARMS fit these rules too well for them not to be intentional. (I considered JURYPERSON initially, until I stumbled upon one that actually ended in 'R' rather than merely containing it...)
Despite these, I think this must be pretty darn close to the OP's intention, hence my posting this answer after almost 2 months of remaining unanswered.
One final note on the choice to go 'in the middle':
I chose the one cluing 'WORLDS' because this is what the other boxes surrounding it clue, but an argument could also be made for '2 THE SUNSHINE STATE' - not because of Florida, but because these planets go around the SUN...