The exact number will be very hard to find, but I can try to calculate a ballpark figure by making some simplifying assumptions.
The simplest is to assume that each adjacency is independent of any other, and has a probability of $1/6$ of having matching colours. There are $6\cdot12=72$ adjacent pairs of stickers, so there is a probability of about $(5/6)^{72}\approx 0.000002$ of having no matching colours anywhere. In other words, out of every million positions about $2$ have no matching colours.
We can do a slightly better approximation by looking at pairs of adjacencies. The probability of an edge not matching either of the adjacent centres is not $(5/6)^2$, but $17/24$ because there are $24$ ways to place the edge and $7$ of them have at least one matching centre. Similarly, of the $24$ ways to place a corner next to a particular side of an edge, $17$ have no matchings. This leads to a probability of $(17/24)^{36}$ for the whole cube to have no matchings, or about $4$ in a million.
Of course this still rests on the assumption that these $36$ pairs of adjacencies are independent of each other, so the actual value is slightly higher still, but it is in the right ballpark.