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I form especially close bonds with others.
Remove my infix, and my superior quality is apparent.
Remove my suffix, and you will become sick of me.
Add a Cl to many of me, and I will burn your house and the ground below it.

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I think you are

FLUORINE.

I form especially close bonds with others.

True. (Chemical bonds, of course.)

Remove my infix, and my superior quality is apparent.

That's FINE.

Remove my suffix, and you will become sick of me.

Time was, the contagious illness everyone worried about getting was the FLU.

Add a Cl to many of me, and I will burn your house and the ground below it.

As the wise man saith, "Sand won't save you this time".

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  • $\begingroup$ The last clue kinda gave it away didn't it? $\endgroup$ – justhalf Apr 28 at 3:07
  • $\begingroup$ It really did :-). $\endgroup$ – Gareth McCaughan Apr 28 at 10:36

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