Is it
A fox?
I run wild and free,
with oh so much glee.
A fox usually is hardly tamed.
I can have many fur colors, all are fluffy,
once you meet me, you'll know I'm a toughie.
Foxes are fluffy. They can survive in very cold places so they are tough(arctic fox) and have different fur colours like white, brown and red.
My cold soul opens to the kind,
you'll find me with a warm mind.
Foxes can live in cold places (cold soul) but they can be warm?
I am a small one,
but your heart will be won.
Foxes are small. Foxes I think are sorta cute?
The wild is my life,
a human home will bring strife.
Foxes are wild animals.
Or maybe (2nd answer)
A wolf?
I run wild and free,
with oh so much glee.
A wolf usually isn't as easily tamed.
I can have many fur colors, all are fluffy,
once you meet me, you'll know I'm a toughie.
A wolves can be fluffy. They are usually thought to be tough animals and will fight(tough).
My cold soul opens to the kind,
you'll find me with a warm mind.
Wolves can be found in colder places, but they are warm-blooded creatures.
I am a small one,
but your heart will be won.
Wolves are smallish compared to things like bears and people.
The wild is my life,
a human home will bring strife.
Wolves might act aggresive to people and they are usually wild.
Bonus hint for either
the acrostic spell IIMIT which might be I'm it and their picture looks wolfy and foxish(their pic has 2 tails though)?